Research Area A
In Research Area A, we will identify key factors that mediate the transition from health to autoimmunity and ultimately to the clinical manifestation of autoimmune disease. This will be the basis for the development of sensitive and specific biomarkers. For subsequent clinical translation, especially in diagnostics, we have a long- standing cooperation with industry partners.
Details for each project are provided on the left.
- Projects
- 1st Generation
- A: Defining Autoimmune Pre-Disease
- A1: Define the impact of shift work on autoimmunity and autoimmune diseases
- A2: B cells as drivers towards clinical SLE manifestation
- A3: G protein-coupled receptors orchestrating granulocytes in pemphigoid diseases
- A4: Epitope-dependent autoantibody-mediated skin inflammation in pemphigoid disease
- A5: Chronic danger signaling as driver of autoimmunity in granulomatosis with polyangiitis
- A6: T cell memory differentiation in early autoimmune disease
- A7: CD4+ T cell receptor sequences during progression towards experimental pemphigoid.
- A8: The C5aR2 pathway as a checkpoint for B cell activation in autoimmunity.
- A9: Genetic and molecular similarity of autoimmune disease
- B: Targeting of Autoimmune Pre-Disease
- Associated projects
- MD projects
- Concluded Projects
- A: Defining Autoimmune Pre-Disease
- 2nd Generation
- 1st Generation
