Ass. TP A2: Unravel Principles of Self-Organization in Injured Tissue
The project focus on the pemphigus vulgaris, combing the Fluid Force Microscopy, omics data (transcriptomic, epigenomic and proteomic), and integrative data analysis and modeling to reveal the mechanism that driving the tissue remodeling during injury. This will help develop the novel treatment approaches, which will benefit not only PV, but also other severe human inflammatory and neoplastic diseases.
- Projects
- 1st Generation
- A: Defining Autoimmune Pre-Disease
- B: Targeting of Autoimmune Pre-Disease
- Associated projects
- Ass. TP A1 - Unravel principles of the biomolecular network in pemphigus vulgaris
- Ass. TP A2: Unravel Principles of Self-Organization in Injured Tissue
- Ass.TP A3 - Landscape of the kinome of several organs of mice of different ages and sexes
- Ass. TP A4 - Complement C3 as key driver of pemphigoid disease pathogenesis
- Ass. TP. A5 - Crosstalk between T cells and B cells in the differentiation of pathogenic plasma cells in pemphigoid diseases
- Ass. TP A6 - Skin-infiltrating T and B cells in the pathogenesis of pemphigoid diseases
- Ass. TP A7- Stromal regulation of inflammation in pemphigoid diseases
- Ass. TP A8 - The role of neutrophils in the regulation of the adaptive immunity in pemphigoid diseases
- Ass.TP B1 - Kinase cascades in neutrophils as therapeutic target in pemphigoid disease
- MD projects
- Concluded Projects
- 2nd Generation
- 1st Generation